Ena/VASP proteins are powerful actin Ferrite polymerases that drive the processive elongation of actin filaments.Members of this protein family have been implicated in a variety of important cellular processes including axon guidance, cell migration and adhesion.However, the specific function of these proteins in macroendocytosis, comprising macrop
Transcriptomic analysis reveals yolk accumulation mechanism from the hepatopancreas to ovary in the pacific white shrimp Litopenaeus vannamei
The Pacific white shrimp Litopenaeus vannamei is an economically important penaeid species worldwide.Under farming conditions, the full ovarian maturation of L.vannamei generally depends on the combination of artificial ablation of unilateral eyestalk and feeding high-quality natural diets, suggesting that nutrient accumulation is important to ovar
Reprogramming of iron metabolism confers ferroptosis resistance in ECM-detached cells
Summary: Cancer cells often acquire resistance to cell death programs induced by loss of integrin-mediated attachment to extracellular matrix (ECM).Given that Canopy adaptation to ECM-detached conditions can facilitate tumor progression and metastasis, there is significant interest in effective elimination of ECM-detached cancer cells.Here, we find
Axonal Protection by Oral Nicotinamide Riboside Treatment with Upregulated AMPK Phosphorylation in a Rat Glaucomatous Degeneration Model
Nicotinamide riboside Classic Cap (NR), a precursor of nicotinamide adenine dinucleotide (NAD+), has been studied to support human health against metabolic stress, cardiovascular disease, and neurodegenerative disease.In the present study, we investigated the effects of oral NR on axonal damage in a rat ocular hypertension model.Intraocular pressur